CJC-1295: An Overview of the Research

CJC-1295 is one of the most frequently studied growth-hormone-axis peptides in research, usually examined alongside Ipamorelin. This guide covers what CJC-1295 is, its mechanism as a GHRH analogue, and how it sits relative to the secretagogues it is paired with.

What Is CJC-1295?

CJC-1295 is a synthetic analogue of Growth Hormone-Releasing Hormone (GHRH) — the signalling peptide that prompts the pituitary to release growth hormone in natural pulses. Sequence modifications give it greater stability than native GHRH, which makes it useful for studying the timing and duration of GHRH signalling. Some versions include a Drug Affinity Complex (DAC) modification that further extends stability.

How Does CJC-1295 Work?

As a GHRH analogue, CJC-1295 is studied for its interaction with the GHRH receptor on the pituitary. Because it acts on the GHRH side of the growth-hormone axis, it is frequently grouped with and studied against ghrelin-receptor compounds such as Ipamorelin, which act on a different point of the same axis.

CJC-1295 vs Ipamorelin

The two are complementary in mechanism: CJC-1295 is a GHRH analogue; Ipamorelin is a selective ghrelin-receptor secretagogue. Studying them together lets researchers examine how the two signalling routes interact across the growth-hormone axis.

Forms, Purity and Handling

• Format: lyophilised powder.

• Purity: greater than or equal to 99% by HPLC.

• COA: per batch.

• Storage: frozen for long-term stability; refrigerated once in solution.

Frequently Asked Questions

What is CJC-1295?

A synthetic analogue of Growth Hormone-Releasing Hormone (GHRH), studied for its stability relative to native GHRH.

What is the DAC modification?

A Drug Affinity Complex modification on some CJC-1295 versions that further extends the compound's stability.

Why is CJC-1295 studied with Ipamorelin?

They act on different points of the growth-hormone axis — GHRH receptor vs ghrelin receptor.

What purity should CJC-1295 be?

Greater than or equal to 99% by HPLC with a per-batch COA.

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